The Journal of Experimental Medicine
PBL InterferonSource
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ON THE COVER
Linear groups of T cell receptors (TCRs), but not single TCRs, respond to low doses of antigen. Activation induced phosphorylation of one TCR might facilitate phosphorylation of the neighboring TCR, creating a domino-like effect and maximizing an otherwise weak signal. Graphic art by New York artist Dan Durso (durso10@yahoo.com). Related article by Schamel et al. See page 493
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