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Cover picture: The preponderance of past experiments on Yersinia pathogenesis has focused on the effects of the Yersinia outer membrane proteins (Yops) in epithelial cells and macrophage, as illustrated here. The related article in this issue by Yao et al., pp. 13431350, demonstrates the rapid and essential role of YopH in inactivating T cell and B cell signaling. 13431350.
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