The Journal of Experimental Medicine
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 Apr 20 1998; 187 (8)

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Commentaries:Back

New Paths in Human Cancer Serology
Lloyd J. Old and Yao-Tseng Chen
J. Exp. Med. 1998 187: 1163-1167. [Full Text] [PDF]  

 

Articles:Back

The Normal Counterpart of IgD Myeloma Cells in Germinal Center Displays Extensively Mutated IgVH Gene, Cµ-Cdelta Switch, and lambda  Light Chain Expression
Christophe Arpin, Odette de Bouteiller, Diane Razanajaona, Isabelle Fugier-Vivier, Francine Brière, Jacques Banchereau, Serge Lebecque, and Yong-Jun Liu
J. Exp. Med. 1998 187: 1169-1178. [Abstract] [Full Text] [PDF]  

T Cell Receptor (TCR) Engagement in Apoptosis-defective, but Interleukin 2 (IL-2)-producing, T Cells Results in Impaired ZAP70/CD3-zeta Association
Almudena G. Sahuquillo, Anne Roumier, Emma Teixeiro, Rafael Bragado, and Balbino Alarcón
J. Exp. Med. 1998 187: 1179-1192. [Abstract] [Full Text] [PDF]  

T Helper 1 (Th1) and Th2 Characteristics Start to Develop During T Cell Priming and Are Associated with an Immediate Ability to Induce Immunoglobulin Class Switching
Kai-Michael Toellner, Sanjiv A. Luther, Daniel M.-Y. Sze, Richard K.-W. Choy, Dale R. Taylor, Ian C.M. MacLennan, and Hans Acha-Orbea
J. Exp. Med. 1998 187: 1193-1204. [Abstract] [Full Text] [PDF]  

Conversion of Membrane-bound Fas(CD95) Ligand to Its Soluble Form Is Associated with Downregulation of Its Proapoptotic Activity and Loss of Liver Toxicity
Pascal Schneider, Nils Holler, Jean-Luc Bodmer, Michael Hahne, Karl Frei, Adriano Fontana, and Jürg Tschopp
J. Exp. Med. 1998 187: 1205-1213. [Abstract] [Full Text] [PDF]  

Aminooxypentane-RANTES Induces CCR5 Internalization but Inhibits Recycling: A Novel Inhibitory Mechanism of HIV Infectivity
Matthias Mack, Bruno Luckow, Peter J. Nelson, Josef Cihak, Graham Simmons, Paul R. Clapham, Nathalie Signoret, Mark Marsh, Manfred Stangassinger, Fréderic Borlat, Timothy N.C. Wells, Detlef Schlöndorff, and Amanda E.I. Proudfoot
J. Exp. Med. 1998 187: 1215-1224. [Abstract] [Full Text] [PDF]  

T Cell-mediated Pathology in Two Models of Experimental Colitis Depends Predominantly on the Interleukin 12/Signal Transducer and Activator of Transcription (Stat)-4 Pathway, but Is Not Conditional on Interferon gamma  Expression by T Cells
Stephen J. Simpson, Samir Shah, Martina Comiskey, Ype P. de Jong, Baoping Wang, Emiko Mizoguchi, Atul K. Bhan, and Cox Terhorst
J. Exp. Med. 1998 187: 1225-1234. [Abstract] [Full Text] [PDF]  

Involvement of Bruton's Tyrosine Kinase in Fcepsilon RI-dependent Mast Cell Degranulation and Cytokine Production
Daisuke Hata, Yuko Kawakami, Naoki Inagaki, Chris S. Lantz, Toshio Kitamura, Wasif N. Khan, Mari Maeda-Yamamoto, Toru Miura, Wei Han, Stephen E. Hartman, Libo Yao, Hiroichi Nagai, Anne E. Goldfeld, Frederick W. Alt, Stephen J. Galli, Owen N. Witte, and Toshiaki Kawakami
J. Exp. Med. 1998 187: 1235-1247. [Abstract] [Full Text] [PDF]  

CD3 Ligation on Immature Thymocytes Generates Antagonist-like Signals Appropriate for CD8 Lineage Commitment, Independently of  T Cell Receptor Specificity
M. Albert Basson, Ursula Bommhardt, Michael S. Cole, J. Yun Tso, and Rose Zamoyska
J. Exp. Med. 1998 187: 1249-1260. [Abstract] [Full Text] [PDF]  

The Permeability Transition Pore Complex: A Target for Apoptosis Regulation by Caspases and Bcl-2-related Proteins
Isabel Marzo, Catherine Brenner, Naoufal Zamzami, Santos A. Susin, Gisela Beutner, Dieter Brdiczka, René Rémy, Zhi-Hua Xie, John C. Reed, and Guido Kroemer
J. Exp. Med. 1998 187: 1261-1271. [Abstract] [Full Text] [PDF]  

Extent of Laminin-5 Assembly and Secretion Effect Junctional Epidermolysis Bullosa Phenotype
Chihiro Matsui, Phyllis Pereira, C. Kathy Wang, Charlotte F. Nelson, Timothy Kutzkey, Caroline Lanigan, David Woodley, Masaaki Morohashi, Elizabeth A. Welsh, and Warren K. Hoeffler
J. Exp. Med. 1998 187: 1273-1283. [Abstract] [Full Text] [PDF]  

Identification of a Human Enterocyte Lipoxin A4 Receptor That Is Regulated by Interleukin (IL)-13 and Interferon gamma  and Inhibits Tumor Necrosis Factor alpha -induced IL-8 Release
Karsten Gronert, Andrew Gewirtz, James L. Madara, and Charles N. Serhan
J. Exp. Med. 1998 187: 1285-1294. [Abstract] [Full Text] [PDF]  

Turnover of CD4+ and CD8+ T Lymphocytes in HIV-1 Infection as Measured by Ki-67 Antigen
Nicolas Sachsenberg, Alan S. Perelson, Sabine Yerly, Gérard A. Schockmel, Dominique Leduc, Bernard Hirschel, and Luc Perrin
J. Exp. Med. 1998 187: 1295-1303. [Abstract] [Full Text] [PDF]  

Impaired Interleukin 4 Signaling in T Helper Type 1 Cells
Hua Huang and William E. Paul
J. Exp. Med. 1998 187: 1305-1313. [Abstract] [Full Text] [PDF]  

CD40 Ligand Is Not Essential for Induction of Type 1 Cytokine Responses or Protective Immunity after Primary or Secondary Infection With Histoplasma capsulatum
Ping Zhou and Robert A. Seder
J. Exp. Med. 1998 187: 1315-1324. [Abstract] [Full Text] [PDF]  

B-1 Cell Development: Evidence for an Uncommitted Immunoglobulin (Ig)M+ B Cell Precursor in B-1 Cell Differentiation
Stephen H. Clarke and Larry W. Arnold
J. Exp. Med. 1998 187: 1325-1334. [Abstract] [Full Text] [PDF]  

Tolerization of Anti-Galalpha 1-3Gal Natural Antibody-forming B Cells by Induction of Mixed Chimerism
Yong-Guang Yang, Emil deGoma, Hideki Ohdan, Jennifer L. Bracy, Yuanxin Xu, John Iacomini, Aron D. Thall, and Megan Sykes
J. Exp. Med. 1998 187: 1335-1342. [Abstract] [Full Text] [PDF]  

 

Brief Definitive Reports:Back

A Double-Edged Kinase Lyn: A Positive and Negative Regulator for Antigen Receptor-mediated Signals
Hirofumi Nishizumi, Keisuke Horikawa, Irena Mlinaric-Rascan, and Tadashi Yamamoto
J. Exp. Med. 1998 187: 1343-1348. [Abstract] [Full Text] [PDF]  

A Survey of the Humoral Immune Response of Cancer Patients to a Panel of Human Tumor Antigens
Elisabeth Stockert, Elke Jäger, Yao-Tseng Chen, Matthew J. Scanlan, Ivan Gout, Julia Karbach, Michael Arand, Alexander Knuth, and Lloyd J. Old
J. Exp. Med. 1998 187: 1349-1354. [Abstract] [Full Text] [PDF]  

Requirement of SH2-containing Protein Tyrosine Phosphatases SHP-1 and SHP-2 for Paired Immunoglobulin-like Receptor B (PIR-B)-mediated Inhibitory Signal
Akito Maeda, Mari Kurosaki, Masao Ono, Toshiyuki Takai, and Tomohiro Kurosaki
J. Exp. Med. 1998 187: 1355-1360. [Abstract] [Full Text] [PDF]  

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