Central role of immunoglobulin (Ig) E in the induction of lung eosinophil infiltration and T helper 2 cell cytokine production: inhibition by a non-anaphylactogenic anti-IgE antibody
AJ Coyle, K Wagner, C Bertrand, S Tsuyuki, J Bews, and C Heusser
J. Exp. Med. 1996 183: 1303-1310.
[Abstract][PDF]
Endogenous altered peptide ligands can affect peripheral T cell responses
K Vidal, BL Hsu, CB Williams, and PM Allen
J. Exp. Med. 1996 183: 1311-1321.
[Abstract][PDF]
The altered tumoricidal capacity of macrophages isolated from tumor- bearing mice is related to reduce expression of the inducible nitric oxide synthase gene
MR Dinapoli, CL Calderon, and DM Lopez
J. Exp. Med. 1996 183: 1323-1329.
[Abstract][PDF]
Major histocompatibility complex class II-associated p41 invariant chain fragment is a strong inhibitor of lysosomal cathepsin L
T Bevec, V Stoka, G Pungercic, I Dolenc, and V Turk
J. Exp. Med. 1996 183: 1331-1338.
[Abstract][PDF]
CD4+ T cell activation and tolerance induction in B cell knockout mice
JA Phillips, CG Romball, MV Hobbs, DN Ernst, L Shultz, and WO Weigle
J. Exp. Med. 1996 183: 1339-1344.
[Abstract][PDF]
Impaired neutrophil response and CD4+ T helper cell 1 development in interleukin 6-deficient mice infected with Candida albicans
L Romani, A Mencacci, E Cenci, R Spaccapelo, C Toniatti, P Puccetti, F Bistoni, and V Poli
J. Exp. Med. 1996 183: 1345-1355.
[Abstract][PDF]
Therapy of murine tumors with p53 wild-type and mutant sequence peptide- based vaccines
JI Mayordomo, DJ Loftus, H Sakamoto, CM De Cesare, PM Appasamy, MT Lotze, WJ Storkus, E Appella, and AB DeLeo
J. Exp. Med. 1996 183: 1357-1365.
[Abstract][PDF]
Visualization, characterization, and turnover of CD8+ memory T cells in virus-infected hosts
C Zimmerman, K Brduscha-Riem, C Blaser, RM Zinkernagel, and H Pircher
J. Exp. Med. 1996 183: 1367-1375.
[Abstract][PDF]
Concurrent engagement of CD40 and the antigen receptor protects naive and memory human B cells from APO-1/Fas-mediated apoptosis
C Lagresle, P Mondiere, C Bella, PH Krammer, and T Defrance
J. Exp. Med. 1996 183: 1377-1388.
[Abstract][PDF]
Modulation of renal disease in autoimmune NZB/NZW mice by immunization with bacterial DNA
GS Gilkeson, P Ruiz, AM Pippen, AL Alexander, JB Lefkowith, and DS Pisetsky
J. Exp. Med. 1996 183: 1389-1397.
[Abstract][PDF]
The function of the soluble interleukin 6 (IL-6) receptor in vivo: sensitization of human soluble IL-6 receptor transgenic mice towards IL- 6 and prolongation of the plasma half-life of IL-6
M Peters, S Jacobs, M Ehlers, P Vollmer, J Mullberg, E Wolf, G Brem, KH Meyer zum Buschenfelde, and S Rose-John
J. Exp. Med. 1996 183: 1399-1406.
[Abstract][PDF]
Requirement of Lyn and Syk tyrosine kinases for the prevention of apoptosis by cytokines in human eosinophils
S Yousefi, DC Hoessli, K Blaser, GB Mills, and HU Simon
J. Exp. Med. 1996 183: 1407-1414.
[Abstract][PDF]
LFA-1-deficient mice show normal CTL responses to virus but fail to reject immunogenic tumor
R Schmits, TM Kundig, DM Baker, G Shumaker, JJ Simard, G Duncan, A Wakeham, A Shahinian, A van der Heiden, MF Bachmann, PS Ohashi, TW Mak, and DD Hickstein
J. Exp. Med. 1996 183: 1415-1426.
[Abstract][PDF]
Mice deficient in IL-1beta manifest impaired contact hypersensitivity to trinitrochlorobenzone
LP Shornick, P De Togni, S Mariathasan, J Goellner, J Strauss-Schoenberger, RW Karr, TA Ferguson, and DD Chaplin
J. Exp. Med. 1996 183: 1427-1436.
[Abstract][PDF]
Different superantigens interact with distinct sites in the Vbeta domain of a single T cell receptor
SC Hong, G Waterbury, and CA Janeway, Jr
J. Exp. Med. 1996 183: 1437-1446.
[Abstract][PDF]
The role of interleukin 12 and nitric oxide in the development of spontaneous autoimmune disease in MRLMP-lprlpr mice
FP Huang, GJ Feng, G Lindop, DI Stott, and FY Liew
J. Exp. Med. 1996 183: 1447-1459.
[Abstract][PDF]
Chronic inflammation caused by lymphotoxin is lymphoid neogenesis
A Kratz, A Campos-Neto, MS Hanson, and NH Ruddle
J. Exp. Med. 1996 183: 1461-1472.
[Abstract][PDF]
Distinct regulatory roles of lymphocyte costimulatory pathways on T helper type-2 mediated autoimmune disease
L Biancone, G Andres, H Ahn, A Lim, C Dai, R Noelle, H Yagita, C De Martino, and I Stamenkovic
J. Exp. Med. 1996 183: 1473-1481.
[Abstract][PDF]
Resistance to cutaneous graft-vs.-host disease is not induced in T cell receptor delta gene-mutant mice
T Shiohara, N Moriya, J Hayakawa, S Itohara, and H Ishikawa
J. Exp. Med. 1996 183: 1483-1489.
[Abstract][PDF]
Localization of DNA damage and its role in altered antigen-presenting cell function in ultraviolet-irradiated mice
AA Vink, FM Strickland, C Bucana, PA Cox, L Roza, DB Yarosh, and ML Kripke
J. Exp. Med. 1996 183: 1491-1500.
[Abstract][PDF]
Reactivation of latent leishmaniasis by inhibition of inducible nitric oxide synthase
S Stenger, N Donhauser, H Thuring, M Rollinghoff, and C Bogdan
J. Exp. Med. 1996 183: 1501-1514.
[Abstract][PDF]
Mechanisms of platelet-activating factor-induced lipid body formation: requisite roles for 5-lipoxygenase and de novo protein synthesis in the compartmentalization of neutrophil lipids
PT Bozza, JL Payne, JL Goulet, and PF Weller
J. Exp. Med. 1996 183: 1515-1525.
[Abstract][PDF]
Exochelins of Mycobacterium tuberculosis remove iron from human iron- binding proteins and donate iron to mycobactins in the M. tuberculosis cell wall
J Gobin and MA Horwitz
J. Exp. Med. 1996 183: 1527-1532.
[Abstract][PDF]
Mitochondrial control of nuclear apoptosis
N Zamzami, SA Susin, P Marchetti, T Hirsch, I Gomez-Monterrey, M Castedo, and G Kroemer
J. Exp. Med. 1996 183: 1533-1544.
[Abstract][PDF]
The requirement for proteasome activity class I major histocompatibility complex antigen presentation is dictated by the length of preprocessed antigen
B Yang, YS Hahn, CS Hahn, and TJ Braciale
J. Exp. Med. 1996 183: 1545-1552.
[Abstract][PDF]
Recognition of class I major histocompatibility complex molecules by Ly- 49: specificities and domain interactions
J Brennan, G Mahon, DL Mager, WA Jefferies, and F Takei
J. Exp. Med. 1996 183: 1553-1559.
[Abstract][PDF]
Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes
J Tian, MA Atkinson, M Clare-Salzler, A Herschenfeld, T Forsthuber, PV Lehmann, and DL Kaufman
J. Exp. Med. 1996 183: 1561-1567.
[Abstract][PDF]
The protease inhibitor, N-acetyl-L-leucyl-L-leucyl-leucyl-L- norleucinal, decreases the pool of major histocompatibility complex class I-binding peptides and inhibits peptide trimming in the endoplasmic reticulum
EA Hughes, B Ortmann, M Surman, and P Cresswell
J. Exp. Med. 1996 183: 1569-1578.
[Abstract][PDF]
Localization of the binding site for the monocyte immunoglobulin (Ig) A- Fc receptor (CD89) to the domain boundary between Calpha2 and Calpha3 in human IgA1
L Carayannopoulos, JM Hexham, and JD Capra
J. Exp. Med. 1996 183: 1579-1586.
[Abstract][PDF]
Metabolism of Tac (IL2Ralpha): physiology of cell surface shedding and renal catabolism, and suppression of catabolism by antibody binding
RP Junghans and TA Waldmann
J. Exp. Med. 1996 183: 1587-1602.
[Abstract][PDF]
Major histocompatibility complex class II-expressing endothelial cells induce allospecific nonresponsiveness in naive T cells
FM Marelli-Berg, RE Hargreaves, P Carmichael, A Dorling, G Lombardi, and RI Lechler
J. Exp. Med. 1996 183: 1603-1612.
[Abstract][PDF]
Neonatal peptide exposure can prime T cells and, upon subsequent immunization, induce their immune deviation: implications for antibody vs. T cell-mediated autoimmunity
RR Singh, BH Hahn, and EE Sercarz
J. Exp. Med. 1996 183: 1613-1621.
[Abstract][PDF]
Rabies superantigen as a Vbeta T-dependent adjuvant
E Astoul, M Lafage, and M Lafon
J. Exp. Med. 1996 183: 1623-1631.
[Abstract][PDF]
5(S),15(S)-dihydroxyeicosatetraenoic acid and lipoxin generation in human polymorphonuclear cells: dual specificity of 5-lipoxygenase towards endogenous and exogenous precursors
C Chavis, I Vachier, P Chanez, J Bousquet, and P Godard
J. Exp. Med. 1996 183: 1633-1643.
[Abstract][PDF]
Infection of human immunodeficiency virus 1 transgenic mice with Toxoplasma gondii stimulates proviral transcription in macrophages in vivo
RT Gazzinelli, A Sher, A Cheever, S Gerstberger, MA Martin, and P Dickie
J. Exp. Med. 1996 183: 1645-1655.
[Abstract][PDF]
Breaking self-tolerance in nonobese diabetic mice
WM Ridgway, M Fasso, A Lanctot, C Garvey, and CG Fathman
J. Exp. Med. 1996 183: 1657-1662.
[Abstract][PDF]
Soluble hyaluronan receptor RHAMM induces mitotic arrest by suppressing Cdc2 and cyclin B1 expression
S Mohapatra, X Yang, JA Wright, EA Turley, and AH Greenberg
J. Exp. Med. 1996 183: 1663-1668.
[Abstract][PDF]
T cell receptor usage and fine specificity of human immunodeficiency virus 1-specific cytotoxic T lymphocyte clones: analysis of quasispecies recognition reveals a dominant response directed against a minor in vivo variant
SA Kalams, RP Johnson, MJ Dynan, KE Hartman, T Harrer, E Harrer, AK Trocha, WA Blattner, SP Buchbinder, and BD Walker
J. Exp. Med. 1996 183: 1669-1679.
[Abstract][PDF]
Human intestinal Vdelta1+ lymphocytes recognize tumor cells of epithelial origin
MJ Maeurer, D Martin, W Walter, K Liu, L Zitvogel, K Halusczcak, H Rabinowich, R Duquesnoy, W Storkus, and MT Lotze
J. Exp. Med. 1996 183: 1681-1696.
[Abstract][PDF]
Distinct T cell receptor signaling requirements for perforin- or FasL- mediated cytotoxicity
MT Esser, B Krishnamurthy, and VL Braciale
J. Exp. Med. 1996 183: 1697-1706.
[Abstract][PDF]
CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation
KF Byth, LA Conroy, S Howlett, AJ Smith, J May, DR Alexander, and N Holmes
J. Exp. Med. 1996 183: 1707-1718.
[Abstract][PDF]
Requirement for CD8+ T cells in the development of airway hyperresponsiveness in a marine model of airway sensitization
E Hamelmann, A Oshiba, J Paluh, K Bradley, J Loader, TA Potter, GL Larsen, and EW Gelfand
J. Exp. Med. 1996 183: 1719-1729.
[Abstract][PDF]
The half-life of RAG-1 protein in precursor B cells is increased in the absence of RAG-2 expression
U Grawunder, DG Schatz, TM Leu, A Rolink, and F Melchers
J. Exp. Med. 1996 183: 1731-1737.
[Abstract][PDF]
Circumventing genetic restriction of protection against malaria with multigene DNA immunization: CD8+ cell-, interferon gamma-, and nitric oxide-dependent immunity
DL Doolan, M Sedegah, RC Hedstrom, P Hobart, Y Charoenvit, and SL Hoffman
J. Exp. Med. 1996 183: 1739-1746.
[Abstract][PDF]
Transcriptional regulation of the Icam-1 gene in antigen receptor- and phorbol ester-stimulated B lymphocytes: role for transcription factor EGR1
JS Maltzman, JA Carmen, and JG Monroe
J. Exp. Med. 1996 183: 1747-1759.
[Abstract][PDF]
Patr-A and B, the orthologues of HLA-A and B, present hepatitis C virus epitopes to CD8+ cytotoxic T cells from two chronically infected chimpanzees
H Kowalski, AL Erickson, S Cooper, JD Domena, P Parham, and CM Walker
J. Exp. Med. 1996 183: 1761-1775.
[Abstract][PDF]
A predictable sequential determinant spreading cascade invariably accompanies progression of experimental autoimmune encephalomyelitis: a basis for peptide-specific therapy after onset of clinical disease
M Yu, JM Johnson, and VK Tuohy
J. Exp. Med. 1996 183: 1777-1788.
[Abstract][PDF]
A subclass of dendritic cells kills CD4 T cells via Fas/Fas-ligand- induced apoptosis
G Suss and K Shortman
J. Exp. Med. 1996 183: 1789-1796.
[Abstract][PDF]
Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo
MA Goodell, K Brose, G Paradis, AS Conner, and RC Mulligan
J. Exp. Med. 1996 183: 1797-1806.
[Abstract][PDF]
Newly identified pair of proteasomal subunits regulated reciprocally by interferon gamma
H Hisamatsu, N Shimbara, Y Saito, P Kristensen, KB Hendil, T Fujiwara, E Takahashi, N Tanahashi, T Tamura, A Ichihara, and K Tanaka
J. Exp. Med. 1996 183: 1807-1816.
[Abstract][PDF]
Heterogeneous phenotypes of expression of the NKB1 natural killer cell class I receptor among individuals of different human histocompatibility leukocyte antigens types appear genetically regulated, but not linked to major histocompatibililty complex haplotype
JE Gumperz, NM Valiante, P Parham, LL Lanier, and D Tyan
J. Exp. Med. 1996 183: 1817-1827.
[Abstract][PDF]
The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kappaB
HL Pahl, B Krauss, K Schulze-Osthoff, T Decker, EB Traenckner, M Vogt, C Myers, T Parks, P Warring, A Muhlbacher, AP Czernilofsky, and PA Baeuerle
J. Exp. Med. 1996 183: 1829-1840.
[Abstract][PDF]
Inhibition of interleukin-1 responsiveness by type II receptor gene transfer: a surface "receptor" with anti-interleukin-1 function
F Re, M Sironi, M Muzio, C Matteucci, M Introna, S Orlando, G Penton-Rol, SK Dower, JE Sims, F Colotta, and A Mantovani
J. Exp. Med. 1996 183: 1841-1850.
[Abstract][PDF]
The interaction of macrophage and non-macrophage tropic isolates of HIV- 1 with thymic and tonsillar dendritic cells in vitro
PU Cameron, MG Lowe, F Sotzik, AF Coughlan, SM Crowe, and K Shortman
J. Exp. Med. 1996 183: 1851-1856.
[Abstract][PDF]
Antibody response to a T-dependent antigen requires B cell expression of complement receptors
DA Croix, JM Ahearn, AM Rosengard, S Han, G Kelsoe, M Ma, and MC Carroll
J. Exp. Med. 1996 183: 1857-1864.
[Abstract][PDF]
A life stage of particle-laden rat dendritic cells in vivo: their terminal division, active phagocytosis, and translocation from the liver to the draining lymph
K Matsuno, T Ezaki, S Kudo, and Y Uehara
J. Exp. Med. 1996 183: 1865-1878.
[Abstract][PDF]
Inhibition of Nur77/Nurr1 leads to inefficient clonal deletion of self- reactive T cells
T Zhou, J Cheng, P Yang, Z Wang, C Liu, X Su, H Bluethmann, and JD Mountz
J. Exp. Med. 1996 183: 1879-1892.
[Abstract][PDF]
Inhibition of leukotriene B4-receptor interaction suppresses eosinophil infiltration and disease pathology in a murine model of experimental allergic encephalomyelitis
RP Gladue, LA Carroll, AJ Milici, DN Scampoli, HA Stukenbrok, ER Pettipher, ED Salter, L Contillo, and HJ Showell
J. Exp. Med. 1996 183: 1893-1898.
[Abstract][PDF]
Association of mitogen-activated protein kinases with microtubules in mouse macrophages
A Ding, B Chen, M Fuortes, and E Blum
J. Exp. Med. 1996 183: 1899-1904.
[Abstract][PDF]
Immunoglobulin G3 blocking antibodies to the fungal pathogen Cryptococcus neoformans
G Nussbaum, R Yuan, A Casadevall, and MD Scharff
J. Exp. Med. 1996 183: 1905-1909.
[Abstract][PDF]
The beta subunit of human granulocyte-macrophage colony-stimulating factor receptor forms a homodimer and is activated via association with the alpha subunit
A Muto, S Watanabe, A Miyajima, T Yokota, and K Arai
J. Exp. Med. 1996 183: 1911-1916.
[Abstract][PDF]
Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy
S Valitutti, S Muller, M Dessing, and A Lanzavecchia
J. Exp. Med. 1996 183: 1917-1921.
[Abstract][PDF]
p53 prevents maturation to the CD4+CD8+ stage of thymocyte differentiation in the absence of T cell receptor rearrangement
D Jiang, MJ Lenardo, and C Zuniga-Pflucker
J. Exp. Med. 1996 183: 1923-1928.
[Abstract][PDF]
gamma/delta T cell-deficient mice have impaired mucosal immunoglobulin A responses
K Fujihashi, JR McGhee, MN Kweon, MD Cooper, S Tonegawa, I Takahashi, T Hiroi, J Mestecky, and H Kiyono
J. Exp. Med. 1996 183: 1929-1935.
[Abstract][PDF]
Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 production
DG Motto, SE Ross, J Wu, LR Hendricks-Taylor, and GA Koretzky
J. Exp. Med. 1996 183: 1937-1943.
[Abstract][PDF]
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