Selective binding of self peptides to disease-associated major histocompatibility complex (MHC) molecules: a mechanism for MHC-linked susceptibility to human autoimmune diseases
KW Wucherpfennig and JL Strominger
J. Exp. Med. 1995 181: 1597-1601.
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Expression of c-MYC under the control of GATA-1 regulatory sequences causes erythroleukemia in transgenic mice
RC Skoda, SF Tsai, SH Orkin, and P Leder
J. Exp. Med. 1995 181: 1603-1613.
[Abstract][PDF]
Early interleukin 12 production by macrophages in response to mycobacterial infection depends on interferon gamma and tumor necrosis factor alpha
IE Flesch, JH Hess, S Huang, M Aguet, J Rothe, H Bluethmann, and SH Kaufmann
J. Exp. Med. 1995 181: 1615-1621.
[Abstract][PDF]
Stochastic coreceptor shut-off is restricted to the CD4 lineage maturation pathway
B Lucas, F Vasseur, and C Penit
J. Exp. Med. 1995 181: 1623-1633.
[Abstract][PDF]
Pancreatic islet beta cells drive T cell-immune responses in the nonobese diabetic mouse model
E Larger, C Becourt, JF Bach, and C Boitard
J. Exp. Med. 1995 181: 1635-1642.
[Abstract][PDF]
Intermediate steps in positive selection: differentiation of CD4+8int TCRint thymocytes into CD4-8+TCRhi thymocytes
K Lundberg, W Heath, F Kontgen, FR Carbone, and K Shortman
J. Exp. Med. 1995 181: 1643-1651.
[Abstract][PDF]
Signals through T cell receptor-zeta chain alone are insufficient to prime resting T lymphocytes
T Brocker and K Karjalainen
J. Exp. Med. 1995 181: 1653-1659.
[Abstract][PDF]
Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo
N Zamzami, P Marchetti, M Castedo, C Zanin, JL Vayssiere, PX Petit, and G Kroemer
J. Exp. Med. 1995 181: 1661-1672.
[Abstract][PDF]
Fas and activation-induced Fas ligand mediate apoptosis of T cell hybridomas: inhibition of Fas ligand expression by retinoic acid and glucocorticoids
Y Yang, M Mercep, CF Ware, and JD Ashwell
J. Exp. Med. 1995 181: 1673-1682.
[Abstract][PDF]
Susceptibility to tumors induced by polyoma virus is conferred by an endogenous mouse mammary tumor virus superantigen
AE Lukacher, Y Ma, JP Carroll, SR Abromson-Leeman, JC Laning, ME Dorf, and TL Benjamin
J. Exp. Med. 1995 181: 1683-1692.
[Abstract][PDF]
Trypanosoma cruzi trans-sialidase: enhancement of virulence in a murine model of Chagas' disease
M Chuenkova and ME Pereira
J. Exp. Med. 1995 181: 1693-1703.
[Abstract][PDF]
Intracellular targeting of antigens internalized by membrane immunoglobulin in B lymphocytes
RN Mitchell, KA Barnes, SA Grupp, M Sanchez, Z Misulovin, MC Nussenzweig, and AK Abbas
J. Exp. Med. 1995 181: 1705-1714.
[Abstract][PDF]
Detection of functional class II-associated antigen: role of a low density endosomal compartment in antigen processing
KA Barnes and RN Mitchell
J. Exp. Med. 1995 181: 1715-1727.
[Abstract][PDF]
Invariant chain cleavage and peptide loading in major histocompatibility complex class II vesicles
S Amigorena, P Webster, J Drake, J Newcomb, P Cresswell, and I Mellman
J. Exp. Med. 1995 181: 1729-1741.
[Abstract][PDF]
Soluble CD14 acts as a shuttle in the neutralization of lipopolysaccharide (LPS) by LPS-binding protein and reconstituted high density lipoprotein
MM Wurfel, E Hailman, and SD Wright
J. Exp. Med. 1995 181: 1743-1754.
[Abstract][PDF]
Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4
NG Jacobson, SJ Szabo, RM Weber-Nordt, Z Zhong, RD Schreiber, JE Darnell, Jr, and KM Murphy
J. Exp. Med. 1995 181: 1755-1762.
[Abstract][PDF]
Fibrin regulates neutrophil migration in response to interleukin 8, leukotriene B4, tumor necrosis factor, and formyl-methionyl-leucyl- phenylalanine
JD Loike, J el Khoury, L Cao, CP Richards, H Rascoff, JT Mandeville, FR Maxfield, and SC Silverstein
J. Exp. Med. 1995 181: 1763-1772.
[Abstract][PDF]
Differential ability of isolated H-2 Kb subsets to serve as TCR ligands for allo-specific CTL clones: potential role for N-linked glycosylation
L Shen and KP Kane
J. Exp. Med. 1995 181: 1773-1783.
[Abstract][PDF]
Ly-49-independent natural killer (NK) cell specificity revealed by NK cell clones derived from p53-deficient mice
FM Karlhofer, MM Orihuela, and WM Yokoyama
J. Exp. Med. 1995 181: 1785-1795.
[Abstract][PDF]
Anti-DNA antibodies bind to DNase I
A Puccetti, MP Madaio, G Bellese, and P Migliorini
J. Exp. Med. 1995 181: 1797-1804.
[Abstract][PDF]
Cytokines increase human hemopoietic cell adhesiveness by activation of very late antigen (VLA)-4 and VLA-5 integrins
JP Levesque, DI Leavesley, S Niutta, M Vadas, and PJ Simmons
J. Exp. Med. 1995 181: 1805-1815.
[Abstract][PDF]
H-2M3a violates the paradigm for major histocompatibility complex class I peptide binding
JM Vyas, JR Rodgers, and RR Rich
J. Exp. Med. 1995 181: 1817-1825.
[Abstract][PDF]
The intracellular signal transduction mechanism of interleukin 5 in eosinophils: the involvement of lyn tyrosine kinase and the Ras-Raf-1- MEK-microtubule-associated protein kinase pathway
K Pazdrak, D Schreiber, P Forsythe, L Justement, and R Alam
J. Exp. Med. 1995 181: 1827-1834.
[Abstract][PDF]
HLA DRB4 0101-restricted immunodominant T cell autoepitope of pyruvate dehydrogenase complex in primary biliary cirrhosis: evidence of molecular mimicry in human autoimmune diseases
S Shimoda, M Nakamura, H Ishibashi, K Hayashida, and Y Niho
J. Exp. Med. 1995 181: 1835-1845.
[Abstract][PDF]
Peptide binding specificity of HLA-DR4 molecules: correlation with rheumatoid arthritis association
J Hammer, F Gallazzi, E Bono, RW Karr, J Guenot, P Valsasnini, ZA Nagy, and F Sinigaglia
J. Exp. Med. 1995 181: 1847-1855.
[Abstract][PDF]
CD36 gene transfer confers capacity for phagocytosis of cells undergoing apoptosis
Y Ren, RL Silverstein, J Allen, and J Savill
J. Exp. Med. 1995 181: 1857-1862.
[Abstract][PDF]
T cell receptor repertoire in polymyositis: clonal expansion of autoaggressive CD8+ T cells
A Bender, N Ernst, A Iglesias, K Dornmair, H Wekerle, and R Hohlfeld
J. Exp. Med. 1995 181: 1863-1868.
[Abstract][PDF]
CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2
MH Sayegh, E Akalin, WW Hancock, ME Russell, CB Carpenter, PS Linsley, and LA Turka
J. Exp. Med. 1995 181: 1869-1874.
[Abstract][PDF]
Autoantibodies produced spontaneously by young 1pr mice carry transforming growth factor beta and suppress cytotoxic T lymphocyte responses
DA Rowley, ET Becken, and RM Stach
J. Exp. Med. 1995 181: 1875-1880.
[Abstract][PDF]
Activated macrophages induce structural abnormalities of the T cell receptor-CD3 complex
T Aoe, Y Okamoto, and T Saito
J. Exp. Med. 1995 181: 1881-1886.
[Abstract][PDF]
Mechanism of endotoxin desensitization: involvement of interleukin 10 and transforming growth factor beta
F Randow, U Syrbe, C Meisel, D Krausch, H Zuckermann, C Platzer, and HD Volk
J. Exp. Med. 1995 181: 1887-1892.
[Abstract][PDF]
The stimulatory effects of interleukin (IL)-12 on hematopoiesis are antagonized by IL-12-induced interferon gamma in vivo
VM Eng, BD Car, B Schnyder, M Lorenz, S Lugli, M Aguet, TD Anderson, B Ryffel, and VF Quesniaux
J. Exp. Med. 1995 181: 1893-1898.
[Abstract][PDF]
Proteolytic processing is required for viral superantigen activity
CG Park, MY Jung, Y Choi, and GM Winslow
J. Exp. Med. 1995 181: 1899-1904.
[Abstract][PDF]
The target cell nucleus is not required for cell-mediated granzyme- or Fas-based cytotoxicity
H Nakajima, P Golstein, and PA Henkart
J. Exp. Med. 1995 181: 1905-1909.
[Abstract][PDF]
NKR-P1A is a target-specific receptor that activates natural killer cell cytotoxicity
JC Ryan, EC Niemi, MC Nakamura, and WE Seaman
J. Exp. Med. 1995 181: 1911-1915.
[Abstract][PDF]
Granzyme A is an interleukin 1 beta-converting enzyme
M Irmler, S Hertig, HR MacDonald, R Sadoul, JD Becherer, A Proudfoot, R Solari, and J Tschopp
J. Exp. Med. 1995 181: 1917-1922.
[Abstract][PDF]
Cytotoxic T cells specific for glutamic acid decarboxylase in autoimmune diabetes
P Panina-Bordignon, R Lang, PM van Endert, E Benazzi, AM Felix, RM Pastore, GA Spinas, and F Sinigaglia
J. Exp. Med. 1995 181: 1923-1927.
[Abstract][PDF]
Molecular behavior adapts to context: heparanase functions as an extracellular matrix-degrading enzyme or as a T cell adhesion molecule, depending on the local pH
D Gilat, R Hershkoviz, I Goldkorn, L Cahalon, G Korner, I Vlodavsky, and O Lider
J. Exp. Med. 1995 181: 1929-1934.
[Abstract][PDF]
Circulating allergen-reactive T cells from patients with atopic dermatitis and allergic contact dermatitis express the skin-selective homing receptor, the cutaneous lymphocyte-associated antigen
LF Santamaria Babi, LJ Picker, MT Perez Soler, K Drzimalla, P Flohr, K Blaser, and C Hauser
J. Exp. Med. 1995 181: 1935-1940.
[Abstract][PDF]
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