The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 98, 311-319, Copyright, 1953, by The Rockefeller Institute for Medical Research New York

ARTICLE

THE RELATIONSHIP BETWEEN THE ACUTE PHASE RESPONSE AND ANTIBODY PRODUCTION IN THE RABBIT : I. CORRELATION BETWEEN THE EARLY APPEARANCE OF CX-REACTIVE PROTEIN AND SUBSEQUENT ANTIBODY PRODUCTION



Harrison F. Wood M.D.1

1 From the Hospital of The Rockefeller Institute for Medical Research

It has been found that some rabbits respond to the administration of either human C-reactive protein or human gamma globulin with the production of an acute phase substance, Cx-reactive protein. A correlation was found to exist between the amount of Cx-protein produced and the subsequent production of significant titers of precipitating antibody to the two antigens employed.

Submitted on June 18, 1953


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