The Journal of Experimental Medicine, Vol 96, 513-516,
Copyright, 1952, by The Rockefeller Institute for Medical Research New York
RATE OF CHOLESTEROL SYNTHESIS IN HYPO- AND HYPERTHYROID RATS
Sanford O. Byers Ph.D.1,
Ray H. Rosenman M.D.1,
Meyer Friedman M.D.1, and
Max W. Biggs M.D.1
1 From the Mount Zion Hospital, the Harold Brunn Institute, San Francisco, and the Donner Laboratory of Medical Physics and the Radiation Laboratory, University of California, Berkeley
The rate of cholesterol synthesis, measured by the rate of incorporation of tritium from body water into the cholesterol molecule, was found to be greater than normal in the hyperthyroid rat and below normal in the hypo-thyroid rat.
Submitted on July 2, 1952