The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 96, 425-438, Copyright, 1952, by The Rockefeller Institute for Medical Research New York

ARTICLE

THE SOMATIC ANTIGEN OF A PHAGE-RESISTANT VARIANT OF PHASE II SHIGELLA SONNEI

Walther F. Goebel Ph.D.1 and Margeris A. Jesaitis Sc.D.1

1 From the Laboratories of The Rockefeller Institute for Medical Research

1. A phage-resistant variant of Phase II Shigella sonnei has been isolated and the type-specific antigen from it has been obtained.

2. The antigen of the variant microorganism, II/3, 4, 7, differs from that of the parent Phase II bacillus in serological specificity and in chemical make-up.

3. Although the antigen of Phase II Sh. sonnei inhibits all T phages to which the bacillus is susceptible, that of the variant fails to inhibit T3, T4, and T7.

 Submitted on June 2, 1952


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