The Journal of Experimental Medicine
R&D Systems
  Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Services
Right arrow Email this article
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new content in the JEM
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Korson, R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Korson, R.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
The Journal of Experimental Medicine, Vol 93, 121-128, Copyright, 1951, by The Rockefeller Institute for Medical Research New York

ARTICLE

A MICROSPECTROPHOTOMETRIC STUDY OF RED CELL NUCLEI DURING PYKNOSIS

Roy Korson M.D.1

1 From the Department of Zoology, Columbia University, New York

1. A microspectrophotometric apparatus was used to measure nuclear absorption in fixed and stained human bone marrow smears.

2. The validity of the measurements was established.

3. The total and polymerized desoxyribose nucleic acid (DNA) of erythroblast nuclei were measured in relative units, and a gradual loss of DNA from the red cell nucleus during maturation was noted.

4. The loss in DNA is comparable quantitatively to that occurring during pathological pyknosis in sarcoma cells.

5. The continual loss of nuclear material during erythropoiesis supports the conception that the nucleus disappears by intracellular dissolution, not by extrusion in the intact form.

 Submitted on September 19, 1950


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?




  Home | Help | Feedback | Subscriptions | Archive | Search
TABLE OF CONTENTS