The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 92, 25-34, Copyright, 1950, by The Rockefeller Institute for Medical Research New York

ARTICLE

ON THE NATURE OF THE TOXIC COMPONENT OF THE SOMATIC ANTIGEN OF SHIGELLA PARADYSENTERIAE TYPE Z (FLEXNER)

Chloe Tal Ph.D.1 and Walther F. Goebel Ph.D.1

1 From the Laboratories of The Rockefeller Institute for Medical Research

From the chemical evidence presented it appears that the toxicity associated with the somatic antigen of Type Z Sh. paradysenteriae may be attributed to an entity distinct from the known components of the complex. That this substance is neither the protein, the lipid, nor the carbohydrate component of the antigen is evident. Because of its lability to chemical manipulation, the nature of the toxic component, has not yet been ascertained.

Submitted on April 13, 1950


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