The Journal of Experimental Medicine
Randox
  Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Services
Right arrow Email this article
Right arrow Similar articles in this journal
Right arrow Alert me to new content in the JEM
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by De Robertis, E.
Right arrow Search for Related Content
PubMed
Right arrow Articles by De Robertis, E.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
The Journal of Experimental Medicine, Vol 90, 291-296, Copyright, 1949, by The Rockefeller Institute for Medical Research New York

ARTICLE

AN ELECTRON MICROSCOPE ANALYSIS OF NERVES INFECTED WITH THE B VIRUS

E. De Robertis M.D.1

1 From the Department of Biology, Massachusetts Institute of Technology, Cambridge

Rabbits were infected with B virus in the right gastrocnemius muscle and both sciatic nerves were fixed and analyzed under the electron microscope, after periods varying between 26 and 144 hours.

Starting at 72 hours, a few neurotubules of the right sciatic show the presence of spherical particles, ranging between 300 and 600 Å. The number and size of the particles increase with time and appear to reach a maximum at 144 hours when the paralysis starts. At this moment also the proximal part of the left sciatic nerve shows the presence of dense particles. The relation of the particles with the periodic structure of the neurotubules was studied both in preparations stained in phosphotungstic acid and those shadowed with chromium. The small and medium sized particles are located within the edges of the neurotubules, and the large particles appear to be attached to the neurotubules.

The possible significance of the dense particles is discussed.

 Submitted on June 9, 1949


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?




  Home | Help | Feedback | Subscriptions | Archive | Search
TABLE OF CONTENTS