The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 90, 113-135, Copyright, 1949, by The Rockefeller Institute for Medical Research New York

ARTICLE

ISOLATION FROM CASES OF INFANTILE DIARRHEA OF A FILTRABLE AGENT CAUSING DIARRHEA IN CALVES

Jacob S. Light M.D.1 and Horace L. Hodes M.D.1

1 From Sydenham Hospital, Baltimore City Health Department, and the Department of Pediatrics of the Johns Hopkins University School of Medicine, Baltimore

From instances of diarrhea of the newborn in four separate hospital outbreaks a filtrable agent was isolated which regularly produced diarrhea in calves. This agent appeared to have the characteristics of a filtrable virus.

The four strains of virus isolated in the outbreaks studied appeared to be identical or very closely related.

The virus was not found present in the stools of any of eight normal newborn infants or five normal calves.

Evidence is presented that the virus may be one of the causes of epidemic diarrhea of the newborn.

 Submitted on March 17, 1949


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