The Journal of Experimental Medicine, Vol 89, 425-430,
Copyright, 1949, by The Rockefeller Institute for Medical Research New York
ELECTRON MICROSCOPE STUDIES OF CELLS BY THE METHOD OF REPLICAS
Albert Claude M.D.1
1 From the Laboratories of The Rockefeller Institute for Medical Research
The method of replicas has been applied to the study with the electron microscope of blood cells and bacteria.
The results indicate that the method can reveal details of intracellular structures. Nuclei can be perceived, and also cytoplasmic bodies such as mitochondria and vacuoles.
Submitted on December 15, 1948