The Journal of Experimental Medicine
Torrey Pines Biolabs
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The Journal of Experimental Medicine, Vol 89, 359-368, Copyright, 1949, by The Rockefeller Institute for Medical Research New York

ARTICLE

DIETARY EFFECTS ON ANEMIA PLUS HYPOPROTEINEMIA IN DOGS : II. THE FINDINGS WITH MILK PRODUCTS, WHEAT, AND PEANUT FLOURS AS COMPARED WITH LIVER



F. S. Robscheit-Robbins Ph.D.1 and G. H. Whipple M.D.1

1 From the Department of Pathology, The University of Rochester, School of Medicine and Dentistry, Rochester, New York

Casein (purified or commercial) in this type of experiment falls in the top bracket as a protein consistently favorable for maximal new hemoglobin and plasma protein production in doubly depleted dogs (anemic and hypo-proteinemic).

Lactalbumin is less favorable for total blood protein production and the ratio of plasma protein to hemoglobin is high—that is lactalbumin favors plasma protein production as compared with casein, or is less favorable for hemoglobin production.

Peanut flour (purified or commercial) is less than half as effective as casein in promoting new blood protein production. The ratio of plasma protein to hemoglobin is about the same as casein.

Wheat gluten as tested is distasteful to dogs. It is neither very good nor very poor for blood protein production when it is eaten. There is nothing unusual about the response. Weight loss usually confuses the picture.

Liver stands as a control base line for the above experiments. Its capacity to further hemoglobin and plasma protein production is well established. The production of hemoglobin was about 3 times that of plasma protein in the experiments.

 Submitted on December 2, 1948


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