The Journal of Experimental Medicine
Torrey Pines Biolabs
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The Journal of Experimental Medicine, Vol 88, 355-360, Copyright, 1948, by The Rockefeller Institute for Medical Research New York

ARTICLE

THE EFFECT OF CHICK EMBRYO EXTRACT ON THE GROWTH AND MORPHOLOGY OF TUBERCLE BACILLI

Hubert Bloch M.D.1

1 From the Laboratories of The Rockefeller Institute for Medical Research

Aqueous extracts of 11-day-old chick embryos enhance the growth of tubercle bacilli in oleic acid-albumin media.

These extracts also increase the tendency of virulent strains to exhibit the serpentine pattern of growth and confer this property on avirulent variants which normally grow unoriented in clumps.

Growth in the presence of chick embryo extract slightly increases the virulence of the virulent strains but does not confer virulence on the avirulent variants.

 Submitted on June 22, 1948


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