The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 87, 295-300, Copyright, 1948, by The Rockefeller Institute for Medical Research New York

ARTICLE

IMMUNOCHEMICAL STUDIES ON BLOOD GROUPS : VI. THE CROSS-REACTION BETWEEN TYPE XIV ANTIPNEUMOCOCCAL HORSE SERUM AND PURIFIED BLOOD GROUP A, B, AND O SUBSTANCES FROM HOG AND HUMAN SOURCES



Elvin A. Kabat Ph.D.1, Aaron Bendich Ph.D.1, Ada E. Bezer 1, and Vesta Knaub 1

1 From the Departments of Neurology and Bacteriology, College of Physicians and Surgeons, Columbia University, and the Neurological Institute of New York

Purified blood group A, B, and O substances from hog and human sources precipitate with Type XIV antipneumococcal horse serum and provide an explanation for the observation that Type XIV antibody agglutinates human erythrocytes of all four major blood groups.

Individual preparations of A substance or O substance from either species vary in their capacity to precipitate Type XIV antibody although the hog A substances did not differ in potency toward anti-A. Similarly, no correlation between A activity and reactivity with Type XIV antibody could be found among the human A substances.

 Submitted on December 16, 1947


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