The Journal of Experimental Medicine
Randox
  Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Services
Right arrow Email this article
Right arrow Similar articles in this journal
Right arrow Alert me to new content in the JEM
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lewis, L. A.
Right arrow Articles by Page, I. H.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Lewis, L. A.
Right arrow Articles by Page, I. H.
Social Bookmarking
 Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
The Journal of Experimental Medicine, Vol 86, 185-192, Copyright, 1947, by The Rockefeller Institute for Medical Research New York


ARTICLE

CHANGES IN THE PLASMA PROTEIN PATTERN (TISELIUS ELECTROPHORETIC TECHNIC) OF PATIENTS WITH HYPERTENSION AND DOGS WITH EXPERIMENTAL RENAL HYPERTENSION

Lena A. Lewis Ph.D.1 and Irvine H. Page M.D.1

1 From the Research Division of the Cleveland Clinic Foundation, Cleveland

The plasma protein pattern of patients with uncomplicated essential hypertension showed only slight variations from the normal while that of patients with severely malignant hypertension showed marked shifts. The fibrinogen and ß-globulins were usually elevated beyond the normal range and the albumin decreased. In less severely malignant hypertension, the changes were less marked.

In dogs with experimental renal hypertension, the gamma-globulin level was greatly elevated, and in one animal exhibiting the malignant syndrome ß-globulin and fibrinogen were also increased.

Elevation of ß-globulin seems in some manner associated with the occurrence of severe vascular disease.

Submitted on March 13, 1947


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?




  Home | Help | Feedback | Subscriptions | Archive | Search
TABLE OF CONTENTS