The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 86, 145-152, Copyright, 1947, by The Rockefeller Institute for Medical Research New York

ARTICLE

MULTIPLE VIRUS INFECTION OF SINGLE HOST CELLS

Jerome T. Syverton M.D.1 and George Packer Berry M.D.1

1 From the Department of Bacteriology, The University of Rochester School of Medicine and Dentistry, Rochester, New York

Evidence is presented to show that two or more viruses can simultaneously manifest their characteristic activities within individual epithelial cells of the normal rabbit's cornea. This evidence, together with that previously presented (1, 5, 6), makes plain that multiple virus infection of a single host cell can take place in corneal cells, in the cells of chick embryos, and in those of rabbit tumors, both benign (Shope's papilloma) and malignant.

Certain implications of the findings are discussed.

 Submitted on March 18, 1947


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