The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 84, 223-234, Copyright, 1946, by The Rockefeller Institute for Medical Research New York

ARTICLE

STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : IV. THE SEROLOGICAL AND TOXIC PROPERTIES OF THE SOMATIC ANTIGENS



Ely Perlman M.D.1 and Walther F. Goebel Ph.D.1

1 From the Laboratories of The Rockefeller Institute for Medical Research

1. The toxicity of killed dysentery bacilli can be ascribed to the somatic antigen. Antibodies to intact dysentery bacilli apparently contain no toxin-neutralizing antibodies other than those which precipitate the purified somatic antigen.

2. The serological properties of dysentery bacilli are determined by the specific somatic antigen. The specificity and cross-reactivity of the somatic antigen are dependent upon the carbohydrate moiety of the molecular complex.

 Submitted on May 30, 1946


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