The Journal of Experimental Medicine
StemCell Technologies
  Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Services
Right arrow Email this article
Right arrow Similar articles in this journal
Right arrow Alert me to new content in the JEM
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Nelson, J. B.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Nelson, J. B.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
The Journal of Experimental Medicine, Vol 84, 7-14, Copyright, 1946, by The Rockefeller Institute for Medical Research New York

ARTICLE

STUDIES ON ENDEMIC PNEUMONIA OF THE ALBINO RAT : I. THE TRANSMISSION OF A COMMUNICABLE DISEASE TO MICE FROM NATURALLY INFECTED RATS



John B. Nelson Ph.D.1

1 From the Department of Animal and Plant Pathology of The Rockefeller Institute for Medical Research, Princeton, New Jersey

A specific disease entity was established in white mice by the nasal instillation of lung and exudate suspensions from each of 14 adult albino rats affected with endemic pneumonia.

The induced disease was characterized by pneumonia (96 per cent), otitis media (94 per cent), and rhinitis (30 per cent). It progressed slowly after an incubation period of 7 to 14 days and was attended by a variable mortality which reached 33 per cent in 22 weeks.

Maintenance of the disease was regularly accomplished by direct transmission from mouse to mouse but only by the nasal route and only from the three foci of involvement. It was also transmissible by direct contact but required a prolonged period of exposure.

The relation of the disease to infectious catarrh, which it closely resembles, is discussed.

 Submitted on March 27, 1946


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:



  Home | Help | Feedback | Subscriptions | Archive | Search
TABLE OF CONTENTS