The Journal of Experimental Medicine, Vol 83, 383-400,
Copyright, 1946, by The Rockefeller Institute for Medical Research New York
THE ACTIVATION OF SKIN GRAFTS
Peyton Rous M.D.1
1 From the Laboratories of The Rockefeller Institute for Medical Research
Rabbit skin rendered hyperplastic by various agents showed less tendency than normal skin to contract when sliced off, and when used for grafts it united with the bed more rapidly and was vascularized sooner. The stimulated epidermis proliferated practically at once, and abundantly, to cover adjacent raw surfaces. Also the donor area healed much more swiftly than usual and became infected less often.
Certain grave limitations and hazards encountered during the experiments with hyperplastic grafts are considered.
Submitted on February 20, 1946