The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 83, 105-132, Copyright, 1946, by The Rockefeller Institute for Medical Research New York

ARTICLE

STUDIES ON PNEUMONIA VIRUS OF MICE (PVM) : III. HEMAGGLUTINATION BY THE VIRUS; THE OCCURRENCE OF COMBINATION BETWEEN THE VIRUS AND A TISSUE SUBSTANCE



Edward C. Curnen M.D., Commander1 and Frank L. Horsfall Jr. M:D., Commander1

1 From the United States Navy Research Unit at the Hospital of The Rockefeller Institute for Medical Research

1. The cause for the phenomenon of hemagglutination with heated PVM suspensions has been sought.

2. Evidence in wide variety indicates that the component responsible for hemagglutination is the virus particle itself.

3. The virus is capable of combining with a substance present in lung tissue of certain mammalian host species susceptible to infection by PVM. The occurrence of such combination accounts for a number of unusual properties manifested by this pneumotropic virus.

 Submitted on October 28, 1945


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