The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 82, 1-20, Copyright, 1945, by The Rockefeller Institute for Medical Research New York

ARTICLE

THE EXPERIMENTAL INFECTION OF THE HUMAN BODY LOUSE, PEDICULUS HUMANUS CORPORIS, WITH MURINE AND EPIDEMIC LOUSE-BORNE TYPHUS STRAINS

J. C. Snyder M.D. Lieutenant Colonel1 and C. M. Wheeler Ph.D. Lieutenant Colonel1

1 From the Cairo Unit of the United States of America Typhus Commission, Cairo, Egypt

Experiments are described which demonstrate that human body lice (Pediculus humanus corporis), were infected experimentally with murine and epidemic louse-borne strains of typhus fever by feeding on suitably prepared rabbits. Details of the two methods of infection, the "bleb technique" and the "I.V. technique," are presented.

It is concluded that the experimental infection of human lice with typhus can be accomplished very easily and rapidly with these methods. The possible applications of the method are discussed.

 Submitted on April 5, 1945


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