The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 79, 361-377, Copyright, 1944, by The Rockefeller Institute for Medical Research New York

ARTICLE

INTERFERENCE BETWEEN THE INFLUENZA VIRUSES : I. THE EFFECT OF ACTIVE VIRUS UPON THE MULTIPLICATION OF INFLUENZA VIRUSES IN THE CHICK EMBRYO



James E. Ziegler Jr. M.D., Lieutenant1 and Frank L. Horsfall Jr. M.D., Lieutenant Commander1

1 From the United States Navy Research Unit at the Hospital of The Rockefeller Institute for Medical Research

Reciprocal interference between influenza A, influenza B, and swine influenza viruses has been demonstrated in the chick embryo. Certain temporal and quantitative factors which influence the production of interference in this host-virus system have been studied. The implications of these observations in relation to the mechanism by which interference is produced are discussed.

Submitted on January 14, 1944


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