The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 79, 79-88, Copyright, 1944, by The Rockefeller Institute for Medical Research New York

ARTICLE

STUDIES ON THE ANTIGENIC COMPOSITION OF GROUP A HEMOLYTIC STREPTOCOCCI : II. THE OCCURRENCE OF STRAINS IN A GIVEN TYPE CONTAINING M BUT NO T ANTIGEN



Rebecca C. Lancefield Ph.D.1 and Walter A. Stewart M.D. Lieutenant (j.g.)1

1 From the Hospital of The Rockefeller Institute for Medical Research

1. Group A hemolytic streptococci have been described which do not agglutinate in anti-T serum because they lack T antigen.

2. Other strains occur which contain T antigen yet do not agglutinate in anti-T serum because T agglutination is blocked by the presence of large amounts of M substance in the streptococci.

3. Strains belonging to a number of types have been analyzed to determine their antigenic composition with respect to M and T antigens.

 Submitted on September 29, 1943


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