The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 78, 273-283, Copyright, 1943, by The Rockefeller Institute for Medical Research New York


ARTICLE

SUSCEPTIBILITY OF CEBUS CAPUCINA (THE SOUTH AMERICAN RINGTAIL MONKEY) AND CERCOPITHECUS CEPHUS (THE AFRICAN MUSTACHE MONKEY) TO POLIOMYELITIS VIRUS

Joseph L. Melnick Ph.D.1 and John R. Paul M.D.1

1 From the Section of Preventive Medicine, Yale University School of Medicine, New Haven

1. The South American ringtail monkey, Cebus capucina, has been infected with the virus of poliomyelitis as found in ultracentrifuged concentrates from poliomyelitic human stools.

2. This species was also found susceptible to poliomyelitis virus found in rhesus and cynomolgus monkey cords, representing early generations of virus derived from two different human sources and from flies trapped in an epidemic area.

3. The Hartford strain of poliomyelitis has been successfully established in different generations in Cebus capucina monkeys.

4. The African mustache monkey, Cerocopithecus cephus, has been infected with poliomyelitis virus by the intra- and subcutaneous routes as readily as the green African monkey, Cercopithecus aethiops sabaeus, and the rhesus monkey, Macaca mulatta.

Submitted on July 2, 1943


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