The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 78, 225-230, Copyright, 1943, by The Rockefeller Institute for Medical Research New York


ARTICLE

THE DISAPPEARANCE OF PHOSPHATASE FROM THE HYDRONEPHROTIC KIDNEY

Harry A. Wilmer M.D.1

1 From the Department of Pathology, The Medical School, University of Minnesota, Minneapolis

"Alkaline" phosphatase disappears or only remains in small amounts in the rabbit and rat kidney after periods of hydronephrosis of 2 to 5 days or more, following complete obstruction of the ureter. By the use of the Gomori-Takamatsu technique it has been possible to distinguish normally functioning from non-functioning cells, when by ordinary histologic stains the cells are indistinguishable.

Submitted on June 17, 1943


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