The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 77, 521-530, Copyright, 1943, by The Rockefeller Institute for Medical Research New York


ARTICLE

VENEZUELAN EQUINE ENCEPHALOMYELITIS IN MAN

J. Casals M.D.1, Edward C. Curnen M.D. Lieutenant1, and Lewis Thomas M.D. Lieutenant1

1 From the Laboratories of The Rockefeller Institute for Medical Research and the United States Navy Research Unit at the Hospital of The Rockefeller Institute for Medical Research

A filterable agent was isolated from the blood and from washings of the upper respiratory passages of a young laboratory worker during a mild, acute, febrile illness. This agent was identified as a strain of Venezuelan equine encephalomyelitis virus. Circulating specific complement-fixing and neutralizing antibodies not present in sera withdrawn during the acute phase of illness were demonstrated in sera obtained during convalescence. A fellow laboratory worker who became similarly ill simultaneously also developed during convalescence specific circulating antibodies not present prior to illness.

Submitted on March 27, 1943


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