The Journal of Experimental Medicine, Vol 77, 355-358,
Copyright, 1943, by The Rockefeller Institute for Medical Research New York
MORPHOLOGICAL STRUCTURE OF RICKETTSIAE
Harry Plotz M.D.1,
Joseph E. Smadel M.D.1,
Thomas F. Anderson Ph.D.1, and
Leslie A. Chambers Ph.D.1
1 From the Virus Laboratory, Army Medical School, Washington, D. C., and The Eldridge Reeves Johnson Foundation for Medical Physics, University of Pennsylvania, Philadelphia
The morphological structures of the rickettsiae of epidemic and endemic typhus fever, Rocky Mountain spotted fever, and Q fever are similar to one another and to certain bacteria. The rickettsial organisms in common with the elementary bodies of vaccinia virus and all bacteria would appear to have a limiting membrane which surrounds a substance that seems to be protoplasmic in nature; numbers of dense granules are embedded in the inner protoplasm.
Submitted on December 15, 1942