The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 75, 127-134, Copyright, 1942, by The Rockefeller Institute for Medical Research New York

ARTICLE

STUDIES CONCERNING THE SITE OF RENIN FORMATION IN THE KIDNEY : I. THE ABSENCE OF RENIN IN THE AGLOMERULAR KIDNEY OF THE MIDSHIPMAN FISH



Meyer Friedman M.D.1 and A. Kaplan Ph.D.1

1 From the Harold Brunn Institute for Cardiovascular Research, Mount Zion Hospital, San Francisco

1. The absence of glomeruli in the kidney of the midshipman fish (Porichthys notatus) is reported.

2. The detection of renin in the glomerular kidney of the carp, the catfish, and the hog, and the apparent absence of this substance in the aglomerular kidney of the midshipman fish suggest that the tubular portion of the mammalian kidney does not produce or store renin.

 Submitted on October 19, 1941


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