The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 74, 591-600, Copyright, 1941, by The Rockefeller Institute for Medical Research New York

ARTICLE

THE EFFECT OF HIGH PROTEIN DIETS ON EXPERIMENTAL RENAL HYPERTENSION

H. Philipsborn 1, L. N. Katz M.D.1, and S. Rodbard Ph.D.1

1 From the Cardiovascular Department, Michael Reese Hospital, and the Departments of Physiology and Pharmacology, Northwestern University Medical School, Chicago

The effect of high and low protein diets were studied on fourteen dogs in twenty-four different experiments. In only two of these animals, both with moderate renal excretory failure, was a reversible rise in blood pressure elicited by a high protein diet.

The possible mechanisms involved in meeting an increased excretory load are discussed.

 Submitted on August 14, 1941


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