The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 73, 327-333, Copyright, 1941, by The Rockefeller Institute for Medical Research New York

ARTICLE

NEUTRALIZATION OF INFLUENZA A VIRUS BY HUMAN SERUM

Frank L. Horsfall Jr. M.D.1 and Edwin H. Lennette M.D.1

1 From the Laboratories of the International Health Division of The Rockefeller Foundation, New York

A linear relationship exists between the quantity of human serum used and the quantity of influenza A virus neutralized. By means of this relationship it is possible to determine the maximum quantity of virus which a given human serum can neutralize. This quantity, the neutralizing capacity, is a fixed value and, unlike the serum dilution end point, is independent of the amount of virus used in the neutralization test.

Submitted on November 14, 1940


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