The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 72, 697-705, Copyright, 1940, by The Rockefeller Institute for Medical Research New York

ARTICLE

STUDIES OF THE TRANSMISSIBLE AGENT OF THE ROUS CHICKEN SARCOMA I : PRECIPITATION WITH BASIC PROTEINS



David Shemin Ph.D.1, E. E. Sproul M.D.1, and James W. Jobling M.D.1

1 From the Department of Pathology, College of Physicians and Surgeons, Columbia University, New York

The viscosity of Rous sarcoma extracts can be reduced with a polysaccharide enzyme isolated from pneumococcus or testis without destruction of the active agent and thus more concentrated active filtrates can be obtained.

The active agent can be precipitated with basic proteins.

The basic protein can be separated from the components originally coming from the tumor filtrate by electrophoresis.

 Submitted on August 20, 1940


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