The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 71, 635-644, Copyright, 1940, by The Rockefeller Institute for Medical Research New York

ARTICLE

A TYPE-SPECIFIC ANTIGENIC PROTEIN DERIVED FROM THE STAPHYLOCOCCUS

W. F. Verwey Sc.D.1

1 From the Department of Bacteriology of New York University College of Medicine, New York

Chemical extraction of lyophilized and ground staphylococci of type A has yielded a type-specific, antigenic fraction which has been shown to be protein. In precipitin tests this fraction reacts in high dilution with homologous immune sera prepared by the injection of animals either with the whole organisms or with the protein itself. Reactions with sera prepared against heterologous types of staphylococci occur only in low dilutions. The type specificity of this fraction has been found to be entirely independent of that of the type-specific carbohydrate described by Julianelle and Wieghard.

Submitted on February 12, 1940


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