The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 71, 551-562, Copyright, 1940, by The Rockefeller Institute for Medical Research New York

ARTICLE

ON GROUP SPECIFIC A SUBSTANCES : IV. THE SUBSTANCE FROM HOG STOMACH



K. Landsteiner M.D.1 and R. A. Harte 1

1 From the Laboratories of The Rockefeller Institute for Medical Research

An investigation is presented on the A substance contained in swine stomach. Preparations made by several procedures, and largely consisting of carbohydrates, were found by means of the ninhydrin method of Van Slyke and his colleagues to contain amino acids accounting for the bulk of the non-hexosamine nitrogen.

As a working hypothesis the idea is advanced that amino acid structures can play a rôle in the serological specificity of haptens consisting predominantly of polysaccharides.

 Submitted on February 4, 1940


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