The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 71, 169-173, Copyright, 1940, by The Rockefeller Institute for Medical Research New York

ARTICLE

THE THERMAL INACTIVATION TIME AT 41.5°C. OF THREE STRAINS OF HERPES SIMPLEX VIRUS

Ruth A. Boak Ph.D.1, Charles M. Carpenter M.D.1, and Stafford L. Warren M.D.1

1 From the Division of Radiology, Department of Medicine of the University of Rochester School of Medicine and Dentistry, Rochester, New York

1. The thermal inactivation time at 41.5°C. of the H. F. and Frank strains of herpes simplex virus, under the conditions described, was 80 hours.

2. A strain of herpes virus recently recovered from a patient treated with a physically induced fever had a thermal inactivation time of 50 hours at 41.5°C.

3. The neurotropic factor of the H. F. and Frank strains of virus was more resistant to a temperature of 41.5°C. than the dermotropic factor. There was little difference in the thermostability of these two factors of the Go strain.

 Submitted on October 19, 1939


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