The Journal of Experimental Medicine
ROBOSEP
  Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Services
Right arrow Email this article
Right arrow Similar articles in this journal
Right arrow Alert me to new content in the JEM
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Smadel, J. E.
Right arrow Articles by Baird, R. D.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Smadel, J. E.
Right arrow Articles by Baird, R. D.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
The Journal of Experimental Medicine, Vol 71, 43-53, Copyright, 1940, by The Rockefeller Institute for Medical Research New York

ARTICLE

A SOLUBLE ANTIGEN OF LYMPHOCYTIC CHORIOMENINGITIS : II. CHARACTERISTICS OF THE ANTIGEN AND ITS USE IN PRECIPITIN REACTIONS



J. E. Smadel M.D.1, M. J. Wall 1, and R. D. Baird M.D.1

1 From the Hospital of The Rockefeller Institute for Medical Research

The soluble antigen of lymphocytic choriomeningitis which is readily separable from the virus is a relatively stable substance and appears to be of a protein nature. A specific precipitin reaction can be demonstrated when immune serum is added to solutions of antigen which have been freed of certain serologically inactive substances. The complement-fixation and precipitation reactions which occur in the presence of immune serum and non-infectious extracts of splenic tissue obtained from guinea pigs moribund with lymphocytic choriomeningitis seem to be manifestations of union of the same soluble antigen and its antibody. On the other hand, the antisoluble substance antibodies and neutralizing substances appear to be different entities.

Submitted on October 12, 1939


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?




  Home | Help | Feedback | Subscriptions | Archive | Search
TABLE OF CONTENTS