The Journal of Experimental Medicine
Janeway's Immunobiology 7th Edition
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The Journal of Experimental Medicine, Vol 71, 1-11, Copyright, 1940, by The Rockefeller Institute for Medical Research New York


ARTICLE

CHEMICAL STUDIES ON BACTERIAL AGGLUTINATION : V. AGGLUTININ AND PRECIPITIN CONTENT OF ANTISERA TO HAEMOPHILUS INFLUENZA, TYPE B



Hattie E. Alexander M.D.1 and Michael Heidelberger Ph.D.1

1 From the Departments of Pediatrics and Medicine, College of Physicians and Surgeons, Columbia University, and the Presbyterian Hospital, New York

1. The quantitative, absolute methods of agglutinin and precipitin analysis previously developed for antipneumococcus sera have been shown to be applicable to horse and rabbit anti-influenza type B sera and plasmas.

2. With the aid of these methods and improved immunization schedules the antibody content of the rabbit sera has been increased five to ten times.

3. The method recommended for the purification of rabbit antipneumococcus antibody has also been found applicable to rabbit anti-influenza type B sera.

Submitted on October 5, 1939


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