The Journal of Experimental Medicine, Vol 70, 147-158,
Copyright, 1939, by The Rockefeller Institute for Medical Research New York
FAMILIAL MAMMARY TUMORS IN THE RABBIT
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I. CLINICAL HISTORY
Harry S. N. Greene M.D.1
1 From the Department of Animal and Plant Pathology of The Rockefeller Institute for Medical Research, Princeton, New Jersey
The clinical histories of two different types of familial mammary cancer in the rabbit have been described. In one type, the first clinical sign of breast abnormality was a sudden and intense engorgement and thereafter the disorder passed through stages of cyst formation and benign neoplasia to cancer with metastasis. In the second type, neoplasia originated in clinically normal breast tissue and there was no history of antecedent mammary abnormality.
Submitted on May 9, 1939