The Journal of Experimental Medicine
Symposium on Dendritic Cells
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The Journal of Experimental Medicine, Vol 70, 141-146, Copyright, 1939, by The Rockefeller Institute for Medical Research New York

ARTICLE

PRODUCTION IN MONKEYS OF COMPLEMENT-FIXING ANTIBODIES WITHOUT ACTIVE IMMUNITY BY INJECTION OF KILLED PLASMODIUM KNOWLESI

Monroe D. Eaton M.D.1 and L. T. Coggeshall M.D.1

1 From the Laboratories of the International Health Division of The Rockefeller Foundation, New York

Injection into rhesus monkeys of Plasmodium knowlesi killed by heat, formalin, drying, or freezing and thawing stimulates the production of complement-fixing antibodies, but no demonstrable agglutinating or protective antibodies are formed.

Possible differences in the immunity mechanisms concerned in active infection and in artificial immunization are discussed.

 Submitted on June 8, 1939


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