The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 69, 499-505, Copyright, 1939, by The Rockefeller Institute for Medical Research New York

ARTICLE

THE ANTIBODY RESPONSE TO SWINE INFLUENZA

Carlos T. Rosenbusch D.V.M.1 and Richard E. Shope M.D.1

1 From the Department of Animal and Plant Pathology of The Rockefeller Institute for Medical Research, Princeton, New Jersey

Antibodies that neutralize swine influenza virus became detectible in the serum of swine on the 6th or 7th day after infection with swine influenza. Their appearance corresponded rather closely with clinical recovery. In swine with the milder filtrate disease, neutralizing antibodies did not appear until sometime between the 7th and 10th days. The maximum antibody titers ranged from 1:60 to 1:160 and were attained on from the 14th to the 27th days after infection.

Submitted on November 3, 1938


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