The Journal of Experimental Medicine
Janeway's Immunobiology 7th Edition
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The Journal of Experimental Medicine, Vol 67, 551-574, Copyright, 1938, by The Rockefeller Institute for Medical Research New York

ARTICLE

THE COURSE OF VIRUS-INDUCED RABBIT PAPILLOMAS AS DETERMINED BY VIRUS, CELLS, AND HOST

John G. Kidd M.D.1

1 From the Laboratories of The Rockefeller Institute for Medical Research

An experimental analysis of the factors responsible for the observed differences in the course of virus-induced papillomas of the rabbit has shown that some are referable to the virus, others to the cells, and yet others to host influences. The interplay of these factors affords enlightening illustration of the nature of the cell-virus relationship in virus-induced tumors. Retrogression of the rabbit papillomas appears to be consequent on a generalized resistance of host origin, elicited by and directed against the proliferating, virus-infected cells.

Submitted on January 16, 1938


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