The Journal of Experimental Medicine
Torrey Pines Biolabs
  Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents
This Article
Right arrow Full Text (PDF, 933K)
Right arrow Alert me when this article is cited
Services
Right arrow Email this article
Right arrow Similar articles in this journal
Right arrow Alert me to new content in the JEM
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Smithburn, K. C.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Smithburn, K. C.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
The Journal of Experimental Medicine, Vol 61, 395-410, Copyright, 1935, by The Rockefeller Institute for Medical Research New York

ARTICLE

THE COLONY MORPHOLOGY OF TUBERCLE BACILLI : I. THE PRESENCE OF SMOOTH COLONIES IN STRAINS RECENTLY ISOLATED FROM SOURCES OTHER THAN SPUTUM



Kenneth C. Smithburn M.D.1

1 From the Laboratories of The Rockefeller Institute for Medical Research

1. Smooth, round, shiny, non-granular, and non-spreading colonies have been observed in cultures of virulent tubercle bacilli freshly isolated from eight human sources other than sputum. The classification of six of these strains as of human type was established by inoculation into rabbits and guinea pigs.

2. The 3 per cent NaOH or 6 per cent H2SO4 frequently used in the isolation of tubercle bacilli are definitely unfavorable to the development of smooth colonies.

3. It was observed that smooth colonies are produced in greater number when the pH of the medium (Corper's egg yolk-glycerine) is adjusted to a point near to but slightly on the acid side of neutral.

 Submitted on December 2, 1934


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?




  Home | Help | Feedback | Subscriptions | Archive | Search
TABLE OF CONTENTS