The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 61, 149-155, Copyright, 1935, by The Rockefeller Institute for Medical Research New York

ARTICLE

STUDIES ON ANAPHYLAXIS WITH POLLEN

Clarence Bernstein Jr. M.D.1

1 From the Department of Medicine, Section of Allergy, The University of Chicago, Chicago

1. Guinea pigs injected intracutaneously and subcutaneously with extract of the pollen of burweed marsh-elder in relatively small amounts did not show anaphylactic response to intravenous shock doses of this material 3 weeks later.

2. If, however, the animals were sensitized with horse serum either before, or along with the same pollen injections, they could then be shocked after an interval of 3 weeks with pollen extract alone.

3. The possible rôle of this underlying sensitivity is discussed.

 Submitted on November 4, 1934


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