The Journal of Experimental Medicine
Torrey Pines Biolabs
  Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Services
Right arrow Email this article
Right arrow Similar articles in this journal
Right arrow Alert me to new content in the JEM
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Murphy, J. B.
Right arrow Articles by Sturm, E.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Murphy, J. B.
Right arrow Articles by Sturm, E.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
The Journal of Experimental Medicine, Vol 60, 305-315, Copyright, 1934, by The Rockefeller Institute for Medical Research New York

ARTICLE

THE EFFECT OF A GROWTH-RETARDING FACTOR FROM NORMAL TISSUES ON SPONTANEOUS CANCER OF MICE

James B. Murphy M.D.1 and Ernest Sturm 1

1 From the Laboratories of The Rockefeller Institute for Medical Research

Extracts of desiccated homologous embryo skin and placenta decrease markedly the rate of postoperative local recurrence after the surgical removal of spontaneous cancer of mice. Autografts after a short period of contact with these extracts either failed to grow, or, in the majority of instances, their subsequent growth was definitely retarded. Intraperitoneal injection of the extracts was followed by cessation of growth of established tumors in more than two-thirds of the animals treated, and among these many of the tumors regressed and over 20 per cent were completely absorbed. Tumor mice treated with either extract rarely developed new malignant foci, though this happened frequently in untreated mice.

Submitted on June 20, 1934


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:



  Home | Help | Feedback | Subscriptions | Archive | Search
TABLE OF CONTENTS