The Journal of Experimental Medicine
Janeway's Immunobiology 7th Edition
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The Journal of Experimental Medicine, Vol 60, 287-291, Copyright, 1934, by The Rockefeller Institute for Medical Research New York

ARTICLE

THE MATERNAL TRANSMISSION OF VACCINIAL IMMUNITY IN SWINE : II. THE DURATION OF ACTIVE IMMUNITY IN THE SOW AND OF PASSIVE IMMUNITY IN THE YOUNG



John B. Nelson Ph.D.1

1 From the Department of Animal and Plant Pathology of The Rockefeller Institute for Medical Research, Princeton, N. J.

The protective substances produced by vaccinia virus in swine are transmitted repeatedly to the young by way of the colostrum of the sow. In 2 instances suckling immunity was demonstrable in the young of 6 successive farrowings which numbered 37 and 57 individuals, respectively.

The immunity acquired by suckling began to decline during the 2nd month and was practically negligible by the end of the 3rd month. Vaccinia virus introduced cutaneously during the first few days of life in the passively protected pigs exerted little or no immunizing effect.

 Submitted on June 20, 1934


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