The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 59, 333-346, Copyright, 1934, by The Rockefeller Institute for Medical Research New York

ARTICLE

THE EFFECT OF HEMOGLOBIN INJECTIONS ON ERYTHROPOIESIS AND ERYTHROCYTE SIZE IN RABBITS RENDERED ANEMIC BY BLEEDING

D. K. Miller M.D.1 and C. P. Rhoads M.D.1

1 From the Hospital of The Rockefeller Institute for Medical Research

1. An anemia characterized by increased size of the red blood cells and a high color index was produced in rabbits by repeated bleeding and by the subcutaneous injection of stroma-free hemoglobin solution.

2. The bone marrow of these rabbits reverted to a more primitive stage than did the marrows of rabbits rendered anemic in the same manner but not treated with hemoglobin.

 Submitted on December 13, 1933


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