The Journal of Experimental Medicine
Keystone Symposia
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The Journal of Experimental Medicine, Vol 57, 993-1008, Copyright, 1933, by The Rockefeller Institute for Medical Research New York

ARTICLE

EXPERIMENTAL GRANULOPENIA, DUE TO BACTERIAL TOXINS ELABORATED IN VIVO

Emery Westervelt Dennis Ph.D.1

1 From the Department of Bacteriology, School of Medicine, American University of Beirut, Beirut, Syria

Pyogenic organisms, under conditions simulating a focal infection, are capable of producing in rabbits a granulopenia which may allow generalized infection and death. It is suggested that agranulocytosis in man is due to the action of leucocidin, rather than to a specific microorganism.

Submitted on February 10, 1933


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