The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 56, 493-505, Copyright, 1932, by The Rockefeller Institute for Medical Research New York

ARTICLE

ACTIVE IMMUNIZATION AGAINST POLIOMYELITIS

Maurice Brodie M.D.1

1 From the Department of Bacteriology, McGill University, Montreal, Canada

1. A single intracutaneous inoculation with a subinfective dose of the virus of poliomyelitis produces considerable immunity.

2. Virus-serum combinations produce an appreciable immunity, providing just sufficient serum is used to protect the animal from paralysis. If there is an excess of serum, the degree of immunity is considerably reduced.

 Submitted on June 22, 1932


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