The Journal of Experimental Medicine
R&D Systems
  Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Services
Right arrow Email this article
Right arrow Similar articles in this journal
Right arrow Alert me to new content in the JEM
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Furth, J.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Furth, J.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
The Journal of Experimental Medicine, Vol 55, 479-493, Copyright, 1932, by The Rockefeller Institute for Medical Research New York

ARTICLE

STUDIES ON THE NATURE OF THE AGENT TRANSMITTING LEUCOSIS OF FOWLS : II. FILTRATION OF LEUCEMIC PLASMA



J. Furth M.D.1, H. K. Miller Ph.D.1, and With the Assistance of Charles Breedis

1 From The Henry Phipps Institute, University of Pennsylvania, Philadelphia

The agent transmitting leucosis readily passed all types of silicious filters. Filtration is particularly successful when the plasma is freed from particles and substances that would otherwise obstruct the pores of the filter. Filtration through fine filters seems to be facilitated by preceding filtration through coarse filters.

A comparison of the periods of incubation of leucosis produced by unfiltered plasma and plasma passed through silicious filters shows that as a result of filtration, the incubation periods are somewhat prolonged. This suggests a slight or moderate decrease in the concentration of the transmitting agent in the plasma caused by filtration.

Filtration tests through collodion membranes indicate that the agent transmitting leucosis is much smaller than the virus of bovine pleuropneumonia (250 mµ) and that it approximates the size of bacteriophage.

 Submitted on November 13, 1931


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?




  Home | Help | Feedback | Subscriptions | Archive | Search
TABLE OF CONTENTS